Hydrogenation reaction is widely used in the preparation of
various pharmaceutical intermediates. However, due to the explosive
characteristics of hydrogen, safety accidents frequently occur. Traditional
batch processes, due to poor gas-liquid mixing, lead to long reaction times,
and the operation process is to ensure its safety, it is necessary to
replace the air in the reactor with nitrogen, the workload is large, and the
operation is cumbersome; the operation of the micro-reactor
is simple, and the time for cleaning
the equipment is reduced. The unique umbrella structure improves the mixing
effect of gas, liquid and solid, greatly reducing the reaction time, improving the conversion rate and production
safety.