Amination reaction is widely used in the
preparation of aliphatic amines and aromatic amine compounds. This reaction is
an exothermic reaction. The temperature is
hard to
control, and easy
to occurs coking. The selectivity is not good and there
are many byproducts; the micro-reactor can be very good to mass transfer and heat exchange, strengthen the reaction process, reduce the
amount of ammonia, improving yield and selectivity, saving costs; shorten reaction time; improve the safety of the reaction.